Intramembrane proteases (IMPs) are a novel class of proteases that catalyze the proteolysis inside the membrane and regulate numerous mobile processes in numerous organisms. RseP, an Escherichia coli site-2 protease (S2P) household IMP, is concerned within the regulation of an extracytoplasmic stress response via the cleavage of membrane-spanning anti-stress-response transcription issue (anti-σE) protein RseA. Extracytoplasmic stresses set off a sequential cleavage of RseA, by which first DegS cleaves off its periplasmic area, and RseP catalyzes the second cleavage of RseA. The 2 tandem-arranged periplasmic PDZ (PDZ tandem) domains of RseP function a size-exclusion filter which prevents the entry of an intact RseA into the energetic website of RseP IMP area. Nevertheless, RseP’s substrate recognition mechanism is just not absolutely understood.
Right here, we discovered {that a} periplasmic area of RseP, situated downstream of the PDZ tandem, comprises a phase (named H1) predicted to kind an amphiphilic helix. Bacterial S2P homologs with numerous numbers of PDZ domains have the same amphiphilic helix within the corresponding area. We demonstrated that the H1 phase types {a partially} membrane-embedded amphiphilic helix on the periplasmic floor of the membrane.
Systematic and random mutagenesis analyses revealed that the H1 helix is necessary for the soundness and proteolytic operate of RseP and that mutations within the H1 phase can have an effect on the PDZ-mediated substrate discrimination. Cross-linking experiments urged that H1 instantly interacts with the DegS-cleaved type of RseA. We suggest that H1 acts as an adaptor required for correct association of the PDZ tandem area to carry out its filter operate and for substrate positioning for its environment friendly cleavage.
Tripeptidyl peptidase I promotes human endometrial epithelial cell adhesive capability implying a job in receptivity
The endometrium undergoes cyclic remodelling all through the menstrual cycle in preparation for embryo implantation which happens in a brief window through the mid-secretory part. It’s throughout this quick ‘receptive window’ that the endometrial luminal epithelium acquires adhesive capability allowing blastocysts agency adhesion to the endometrium to determine being pregnant. Dysregulation in any of those steps can compromise embryo implantation leading to implantation failure and infertility. Many elements contribute to those processes together with and proteases.
Tripeptidyl peptidase 1 is a is a lysosomal serine-type protease nevertheless the contribution of the TPP1 to receptivity is unknown. We aimed to research the function of receptivity in people.Within the present research, TPP1 was expressed in each epithelial and stromal compartments of the endometrium throughout the menstrual cycle. Expression was confined to the cytoplasm of luminal and glandular epithelial cells and stromal cells. Staining of mid-secretory endometrial tissues of ladies with regular fertility and first unexplained infertility confirmed lowered immunostaining depth of TPP1 in luminal epithelial cells of infertile tissues in comparison with fertile tissues.
In contrast, TPP1 ranges in glandular epithelial and stromal cells had been comparable in each teams within the mid-secretory part. Inhibition of TPP1 utilizing siRNA compromised HTR8/SVneo (trophoblast cell line) spheroid adhesion on siRNA-transfected Ishikawa cells (endometrial epithelial cell line) in vitro. This impairment was related to decreased sirtuin 1 (SIRT1), BCL2 and p53 mRNA and unaltered and LIF receptor gene expression between remedy teams. siRNA knockdown of TPP1 in main human endometrial stromal cells didn’t have an effect on decidualization nor the expression of decidualization markers prolactin (PRL) and insulin-like development factor-binding protein 1 (IGFBP1). Taken collectively, our knowledge strongly suggests a job for TPP1 in endometrial receptivity by way of its results on epithelial cell adhesion and suggests lowered ranges related to unexplained infertility might contribute to implantation failure.
Involvement of a Membrane-Bound Amphiphilic Helix in Substrate Discrimination and Binding by an Escherichia coli S2P Peptidase RseP
Vildagliptin, a dipeptidyl peptidase-Four inhibitor, reduces betel-nut induced carcinogenesis in feminine mice
Purpose: Betel-nut, a well-liked masticatory amongst Southeast Asian populations is a category I carcinogen, beforehand related to dyslipidemia and aberrant lipid metabolism, and is reported for use extra regularly by females, than males. This research investigates the potential of repurposing the anti-diabetic drug, vildagliptin, a dipeptidyl peptidase-Four inhibitor, for assuaging the oncogenic situation in feminine Swiss Albino mice administered an aqueous extract of betel-nut (AEBN) orally (2 mg ml-1) for 24 weeks.
Primarystrategies: Tissues had been investigated by histopathological, immunohistochemical and apoptosis assays. Biochemical analyses of oxidative stress markers and lipid profile had been carried out utilizing completely different tissues and sera. The expressions of various proteins concerned in lipid metabolism and oncogenic pathways had been evaluated by Western blotting.
) Recombinant Mouse Serpin G1/C1 Inhibitor (C-6His) |
|
CJ07-50ug |
Novoprotein |
50ug |
EUR 595.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl,pH8.0. |
) Recombinant Human Serpin G1/C1 Inhibitor (C-6His) |
|
C539-10ug |
Novoprotein |
10ug |
EUR 187.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
Recombinant Human Serpin G1/C1 Inhibitor (C-6His) |
|
C539-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
Recombinant Human Serpin G1/C1 Inhibitor (C-6His) |
|
C539-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
Recombinant Human Serpin G1/C1 Inhibitor (C-6His) |
|
C539-50ug |
Novoprotein |
50ug |
EUR 442.8 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
 Human Serpin C1/Antithrombin-III PicoKine ELISA Kit |
|
EK1393 |
BosterBio |
96 wells |
EUR 510 |
|
Description: For quantitative detection of human Serpin C1 in cell culture supernates, serum, plasma (heparin, EDTA, citrate) and urine. |
 Recombinant Human Serpin C1/Antithrombin III/ATIII Protein |
|
RP00140 |
Abclonal |
20 μg |
EUR 423.6 |
 Recombinant Human Serpin G1/C1 inhibitor/C1IN Protein |
|
RP00197 |
Abclonal |
10 μg |
EUR 168 |
 anti-C1 Inactivator |
|
YF-PA23327 |
Abfrontier |
50 ul |
EUR 400.8 |
|
Description: Mouse polyclonal to C1 Inactivator |
anti-C1 Inactivator |
|
YF-PA10543 |
Abfrontier |
50 ug |
EUR 435.6 |
|
Description: Mouse polyclonal to C1 Inactivator |
anti-C1 Inactivator |
|
YF-PA10544 |
Abfrontier |
100 ug |
EUR 483.6 |
|
Description: Rabbit polyclonal to C1 Inactivator |
 Human Serpin C1/Antithrombin-III PicoKine™ Fast ELISA Kit |
|
FEK1393 |
BosterBio |
96 wells |
EUR 570 |
|
Description: The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Human Antithrombin Iii/SERPINC1 with <10pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernates, serum, plasma (heparin, EDTA, citrate) and urine. This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Antithrombin Iii/SERPINC1 tissue specificity: Found in plasma. |
 Anti-Serpin B12 Antibody |
|
A13578 |
BosterBio |
100ul |
EUR 476.4 |
|
Description: Rabbit Polyclonal Antibody for Serpin B12 Antibody (SERPINB12) detection. Tested with WB in Human. |
，Member1(SERPING1) ELISA kit) Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E03C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E03C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E03C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Anti-Cytochrome c1 Antibody |
|
A02958 |
BosterBio |
100ul |
EUR 476.4 |
|
Description: Rabbit Polyclonal Antibody for Cytochrome c1 Antibody (CYC1) detection. Tested with WB in Human, Mouse. |
) Anti-plexin C1 (1A12) |
|
YF-MA17154 |
Abfrontier |
100 ug |
EUR 435.6 |
|
Description: Mouse monoclonal to plexin C1 |
) Anti-DNAJB6 (2C11-C1) |
|
YF-MA11237 |
Abfrontier |
100 ug |
EUR 435.6 |
|
Description: Mouse monoclonal to DNAJB6 |
 ELISA Kit) Mouse APO-C1(Apolipoprotein C1) ELISA Kit |
|
EM0844 |
FN Test |
96T |
EUR 571.5 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 37.5 ng/ml |
) Mouse Serpin H1 (Serpinh1) |
|
1-CSB-EP021087MO |
Cusabio |
-
EUR 606.00
-
EUR 318.00
-
EUR 2192.40
-
EUR 919.20
-
EUR 1461.60
-
EUR 402.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Mouse Serpin H1(Serpinh1) expressed in E.coli |
Mouse Serpin H1 (Serpinh1) |
|
1-CSB-YP021087MO |
Cusabio |
-
EUR 604.80
-
EUR 318.00
-
EUR 2198.40
-
EUR 915.60
-
EUR 1459.20
-
EUR 400.80
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Mouse Serpin H1(Serpinh1) expressed in Yeast |
) CLIA kit for Mouse APO-C1 (Apolipoprotein C1) |
|
E-CL-M0099 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
|
|
Description: A sandwich CLIA kit for quantitative measurement of Mouse APO-C1 (Apolipoprotein C1) in samples from Serum, Plasma, Cell supernatant |
 Anti-hnRNP C1/C2 Antibody |
|
A02726 |
BosterBio |
100ul |
EUR 476.4 |
|
Description: Rabbit Polyclonal hnRNP C1/C2 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
) Anti-C1 Inactivator (3F4-1D9) |
|
YF-MA10108 |
Abfrontier |
100 ug |
EUR 435.6 |
|
Description: Mouse monoclonal to C1 Inactivator |
) Anti-Niemann Pick C1 (4H2) |
|
YF-MA10640 |
Abfrontier |
100 ug |
EUR 435.6 |
|
Description: Mouse monoclonal to Niemann Pick C1 |
) Anti-Stefin B (M1-C1) |
|
YF-MA12592 |
Abfrontier |
100 ug |
EUR 435.6 |
|
Description: Mouse monoclonal to Stefin B |
，Member1(SERPING1) ELISA kit) Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E06C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E06C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E06C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E04C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E04C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E04C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E01C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E01C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E01C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E02C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E02C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E02C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E07C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E07C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E07C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Dog Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E08C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E08C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E08C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E09C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E09C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E09C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
，Member1(SERPING1) ELISA kit) Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E05C0353-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E05C0353-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA kit |
|
E05C0353-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
) Anti-Calicheamicin monoclonal antibody (clone c1) |
|
ADC-AD-011 |
Creative Biolabs |
50 μg |
EUR 3528 |
|
Description: A mouse monoclonal antibody (clone c1) which specifically againsts the payload Calicheamicin. This product is for research purposes only, not for use in diagnostics. |
 Mouse Anti-Ovalbumin IgE Monoclonal Antibody, Clone E-C1 |
|
7091 |
Chondrex |
1 mg/ml x 0.1 ml |
EUR 406.26 |
|
Description: Mouse Anti-Ovalbumin IgE Monoclonal Antibody |
 Protein) Mouse Apolipoprotein C1 (APOC1) Protein |
|
20-abx065418 |
Abbexa |
-
EUR 777.60
-
EUR 326.40
-
EUR 2331.60
-
EUR 910.80
-
EUR 560.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Mouse Plexin C1 ELISA kit |
|
E03P1025-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Plexin C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Plexin C1 ELISA kit |
|
E03P1025-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Plexin C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Plexin C1 ELISA kit |
|
E03P1025-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Plexin C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse Apolipoprotein C1 ELISA kit |
|
E03A0514-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Apolipoprotein C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Apolipoprotein C1 ELISA kit |
|
E03A0514-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Apolipoprotein C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Apolipoprotein C1 ELISA kit |
|
E03A0514-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse Apolipoprotein C1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
) Recombinant Mouse Serpin E2 (C-10His) |
|
CU57-10ug |
Novoprotein |
10ug |
EUR 157.2 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM Tris,150 mM NaCl,pH8.0. |
Recombinant Mouse Serpin E2 (C-10His) |
|
CU57-1mg |
Novoprotein |
1mg |
EUR 2008.8 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM Tris,150 mM NaCl,pH8.0. |
Recombinant Mouse Serpin E2 (C-10His) |
|
CU57-500ug |
Novoprotein |
500ug |
EUR 1399.2 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM Tris,150 mM NaCl,pH8.0. |
Recombinant Mouse Serpin E2 (C-10His) |
|
CU57-50ug |
Novoprotein |
50ug |
EUR 327.6 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM Tris,150 mM NaCl,pH8.0. |
 ELISA kit) Mouse Maspin(serpin B5) ELISA kit |
|
E03M0026-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Maspin(serpin B5) ELISA kit |
|
E03M0026-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Maspin(serpin B5) ELISA kit |
|
E03M0026-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Mouse Serpin B10(SERPINB10) ELISA kit |
|
E03S0360-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin B10(SERPINB10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin B10(SERPINB10) ELISA kit |
|
E03S0360-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin B10(SERPINB10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin B10(SERPINB10) ELISA kit |
|
E03S0360-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin B10(SERPINB10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Mouse Serpin H1(SERPINH1) ELISA kit |
|
E03S0361-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin H1(SERPINH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin H1(SERPINH1) ELISA kit |
|
E03S0361-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin H1(SERPINH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Serpin H1(SERPINH1) ELISA kit |
|
E03S0361-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Serpin H1(SERPINH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse Serpin D1 PicoKine ELISA Kit |
|
EK1969 |
BosterBio |
96 wells |
EUR 510 |
|
Description: For quantitative detection of mouse Serpin D1 in cell culture supernates, serum and plasma (EDTA, citrate) and urine. |
 Serpin A6 antibody |
|
70R-12181 |
Fitzgerald |
100 ug |
EUR 483.6 |
|
Description: Rabbit polyclonal Serpin A6 antibody |
 Serpin A1 antibody |
|
70R-50204 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal Serpin A1 antibody |
 Serpin B5 antibody |
|
70R-50205 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal Serpin B5 antibody |
 Serpin B9 antibody |
|
70R-50206 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal Serpin B9 antibody |
 Serpin B4 antibody |
|
70R-50366 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal Serpin B4 antibody |
 Serpin B7 antibody |
|
70R-50630 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal Serpin B7 antibody |
Serpin B5 antibody |
|
70R-33858 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal Serpin B5 antibody |
 Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody |
|
M02726 |
BosterBio |
100ug/vial |
EUR 476.4 |
|
Description: Rabbit Monoclonal hnRNP C1/C2 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
 antibody) Anti-Phospho-hnRNP C1/2 (S260) antibody |
|
STJ90910 |
St John's Laboratory |
200 µl |
EUR 236.4 |
|
Description: Rabbit polyclonal to Phospho-hnRNP C1/2 (S260). |
 ELISA Kit) Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
20-abx153662 |
Abbexa |
-
EUR 7970.40
-
EUR 4250.40
-
EUR 990.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
 CLIA Kit) Mouse Apolipoprotein C1 (APOC1) CLIA Kit |
|
20-abx491288 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
) Mouse Plasma protease C1 inhibitor (Serping1) |
|
1-CSB-EP021086MO |
Cusabio |
-
EUR 606.00
-
EUR 318.00
-
EUR 2192.40
-
EUR 919.20
-
EUR 1461.60
-
EUR 402.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Mouse Plasma protease C1 inhibitor(Serping1),partial expressed in E.coli |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
DLR-APOC1-Mu-48T |
DL Develop |
48T |
EUR 586.8 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Apolipoprotein C1 (APOC1) in samples from serum, plasma or other biological fluids. |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
DLR-APOC1-Mu-96T |
DL Develop |
96T |
EUR 762 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Apolipoprotein C1 (APOC1) in samples from serum, plasma or other biological fluids. |
 Mouse Plexin C1 PicoKine ELISA Kit |
|
EK1829 |
BosterBio |
96 wells |
EUR 510 |
|
Description: For quantitative detection of mouse Plexin C1 in cell culture supernates, serum and plasma (heparin, EDTA). |
 Monoclonal Antibody (Mouse)) Apolipoprotein C1 (APOC1) Monoclonal Antibody (Mouse) |
|
4-MAA252Mu21 |
Cloud-Clone |
-
EUR 303.60
-
EUR 3138.00
-
EUR 778.80
-
EUR 382.80
-
EUR 259.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
|
Description: A Rat monoclonal antibody against Mouse Apolipoprotein C1 (APOC1) |
 Polyclonal Antibody (Mouse)) Apolipoprotein C1 (APOC1) Polyclonal Antibody (Mouse) |
|
4-PAA252Mu01 |
Cloud-Clone |
-
EUR 283.20
-
EUR 2805.60
-
EUR 703.20
-
EUR 352.80
-
EUR 250.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
|
Description: A Rabbit polyclonal antibody against Mouse Apolipoprotein C1 (APOC1) |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
SEA252Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5269.39 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Apolipoprotein C1 (APOC1) in serum, plasma and other biological fluids. |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
SEA252Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 539.12 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Apolipoprotein C1 (APOC1) in serum, plasma and other biological fluids. |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
SEA252Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 718.75 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Apolipoprotein C1 (APOC1) in serum, plasma and other biological fluids. |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
SEA252Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2874.38 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Apolipoprotein C1 (APOC1) in serum, plasma and other biological fluids. |
Mouse Apolipoprotein C1 (APOC1) ELISA Kit |
|
4-SEA252Mu |
Cloud-Clone |
-
EUR 5330.40
-
EUR 2815.20
-
EUR 718.80
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Apolipoprotein C1 (APOC1) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
Key findings: AEBN induced carcinogenesis primarily within the liver by considerably impairing AMPK signaling, inducing oxidative stress, activating Akt/mTOR signaling, growing Ki-67 immunoreactivity and cyclin D1 expression, and considerably diminishing apoptosis. Co-administration of AEBN with vildagliptin (10 mg kg-1 physique weight) for eight weeks lowered liver dysplasia, and considerably decreased free palmitic acid, elevated free oleic acid, normalized lipid profile, decreased oxidative stress, cyclin D1 expression, Ki-67 immunoreactivity, and Bcl2 expression, and elevated the ratio of apoptotic/non-apoptotic cells. Mechanistically, vildagliptin elicited these physiological and molecular alterations by restoring regular AMPK signaling and decreasing the mobile expressions of FASN and HMGCR, restoring AMPK-dependent phosphorylation of p53 at Ser-15 and decreasing Akt/mTOR signaling.
