Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
C1A cysteine peptidases have been proven to play an vital position throughout apicomplexan invasion and egress of host crimson blood cells (RBCs) and due to this fact have been exploited as targets for drug improvement, through which peptidase specificity is deterministic. Babesia bovis genome is presently obtainable and from the 17 putative cysteine peptidases annotated 4 belong to the C1A subfamily. On this examine, we describe the biochemical characterization of a C1A cysteine peptidase, named right here BbCp (B. bovis cysteine peptidase) and consider its potential participation within the parasite asexual cycle in host RBCs.
The recombinant protein was obtained in bacterial inclusion our bodies and after a refolding course of, offered typical kinetic options of the cysteine peptidase household, enhanced exercise within the presence of a decreasing agent, optimum pH between 6.5 and seven.zero and was inhibited by cystatins from R. microplus. Furthermore, rBbCp substrate specificity analysis utilizing a peptide phage show library confirmed a choice for Val > Leu > Phe. Lastly, antibodies anti-rBbCp have been in a position to intervene with B. bovis development in vitro, which highlights the BbCp as a possible goal for drug design. Sign peptides assist newly synthesized proteins attain the cell membrane or be secreted.
As a part of a organic course of key to immune response and surveillance in people, and related to illnesses, e.g. Alzheimer, remnant sign peptides and different transmembrane segments are proteolyzed by the intramembrane aspartyl protease (IAP) enzyme household. Right here, we recognized IAP orthologs all through the tree of life. Along with eukaryotes, IAPs are encoded in metabolically various archaea from a variety of environments. We discovered three distinct clades of archaeal IAPs: (1) Euryarchaeota (e.g. halophilic Halobacteriales, methanogenic Methanosarcinales and Methanomicrobiales, marine Poseidoniales, acidophilic Thermoplasmatales, hyperthermophilic Archaeoglobus spp.), (2) DPANN, and Bathyarchaeota, Crenarchaeota, and Asgard.
Antagonistic occasion profiles of dipeptidyl peptidase-Four inhibitors: knowledge mining of the general public model of the FDA hostile occasion reporting system
Background: To explain and analyze the patterns of hostile occasions related to dipeptidyl peptidase-Four inhibitors (DPP-4is) (sitagliptin, saxagliptin, linagliptin, vildagliptin, and alogliptin) from the FDA Antagonistic Occasion Reporting System (FAERS) and to spotlight areas of security issues.
Strategies: Antagonistic occasions spontaneously submitted to the FAERS between 2004 Q1 to 2019 Q2 have been included. The net software OpenVigil 2.1 was used to question the database. The analysis relied on definitions of most well-liked phrases (PTs) specified by the Medical Dictionary for Regulatory Actions (MedDRA) and the standardized MedDRA Queries (SMQ). The reporting odds ratio (ROR), with 95% confidence intervals (CIs) was calculated for disproportionality evaluation.
Outcomes: Over 16 years, a complete of 9706 hostile occasion stories have been recognized. Alogliptin was excluded from additional evaluation because of inadequate pattern dimension. In contrast with the non-insulin antidiabetic medicine, the 4 DPP-4is have been all disproportionately related to 4 SMQs: “gastrointestinal nonspecific irritation and dysfunctional situations,” “hypersensitivity,” “extreme cutaneous hostile reactions,” and “noninfectious diarrhoea”. As for PT degree analyses, DPP-4is are related to greater reporting of the gastrointestinal tract, pancreas, malignancies, an infection, musculoskeletal issues, common issues, hypersensitivity, and pores and skin AEs.
Conclusions: Information mining of the FAERS is beneficial for inspecting DPP-Four inhibitors-associated hostile occasions. The findings of the current examine are suitable with scientific expertise, and it supplies useful data to decision-makers and healthcare suppliers in scientific follow.
Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
Structural Modeling of Cell Wall Peptidase CwpFM (EntFM) Reveals Distinct Intrinsically Disordered Extensions Particular to Pathogenic Bacillus cereus Strains
The emergence of B. cereus as an opportunistic food-borne pathogen has intensified the necessity to distinguish strains of public well being concern. The heterogeneity of the illnesses related to B. cereus infections emphasizes the flexibility of those micro organism strains to colonize their host. Nonetheless, the molecular foundation of those variations stays unclear. A number of toxins are concerned in virulence, notably in gastrointestinal issues, however there are presently no organic markers in a position to differentiate pathogenic from innocent strains. We’ve beforehand proven that CwpFM is a cell wall peptidase concerned in B. cereus virulence.
Right here, we report a sequence/construction/perform characterization of 39 CwpFM sequences, chosen from a set of B. cereus with various virulence phenotypes, from innocent to extremely pathogenic strains. CwpFM is homology-modeled in silico as an exported papain-like endopeptidase, with an N-terminal finish composed of three successive bacterial Src Homology Three domains (SH3b1-3) more likely to management protein-protein interactions in signaling pathways, and a C-terminal finish that accommodates a catalytic area primed to kind a reliable energetic web site. We confirmed in vitro that CwpFM is an endopeptidase with a average peptidoglycan hydrolase exercise.
Serpin B5 (SERPINB5) Antibody |
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| 20-abx115469 | Abbexa |
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Serpin B5 (SERPINB5) Antibody |
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| 20-abx014060 | Abbexa |
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Serpin B5 (SERPINB5) Antibody |
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| abx038026-100ug | Abbexa | 100 ug | EUR 469.2 |
Serpin B5 (SERPINB5) Antibody |
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| 20-abx127043 | Abbexa |
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Serpin B5 (SERPINB5) Antibody |
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| 20-abx008867 | Abbexa |
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Serpin B5 (SERPINB5) Antibody |
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| 20-abx001093 | Abbexa |
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Polyclonal Serpin B5 Antibody |
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| APR05559G | Leading Biology | 0.1ml | EUR 580.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Serpin B5 . This antibody is tested and proven to work in the following applications: |
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Serpin B5 Conjugated Antibody |
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| C34298 | SAB | 100ul | EUR 476.4 |
Human Serpin B3 Antibody |
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| 32720-05111 | AssayPro | 150 ug | EUR 313.2 |
Human Serpin B8 Antibody |
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| 32735-05111 | AssayPro | 150 ug | EUR 313.2 |
Human Serpin D1 Antibody |
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| 32810-05111 | AssayPro | 150 ug | EUR 313.2 |
Human Serpin B5 (SERPINB5) ELISA Kit |
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| abx250620-96tests | Abbexa | 96 tests | EUR 801.6 |
Human Serpin B5(SERPINB5) ELISA kit |
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| CSB-EL021073HU-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Human Serpin B5 (SERPINB5) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human Serpin B5(SERPINB5) ELISA kit |
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| 1-CSB-EL021073HU | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Serpin B5(SERPINB5) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Human Serpin B5, SERPINB5 ELISA KIT |
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| ELI-03908h | Lifescience Market | 96 Tests | EUR 988.8 |
Human SERPINB5/ Serpin B5 ELISA Kit |
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| E2258Hu | Sunlong | 1 Kit | EUR 685.2 |
Human SERPINB5(Serpin B5) ELISA Kit |
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| EH1350 | FN Test | 96T | EUR 681.12 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
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Recombinant Human Serpin B5/SERPINB5/Maspin |
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| CF94-10ug | Novoprotein | 10ug | EUR 175.2 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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Recombinant Human Serpin B5/SERPINB5/Maspin |
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| CF94-1mg | Novoprotein | 1mg | EUR 2739.6 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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Recombinant Human Serpin B5/SERPINB5/Maspin |
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| CF94-500ug | Novoprotein | 500ug | EUR 1935.6 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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Recombinant Human Serpin B5/SERPINB5/Maspin |
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| CF94-50ug | Novoprotein | 50ug | EUR 363.6 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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ELISA kit for Human Serpin B5 (SERPINB5) |
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| KTE60698-48T | Abbkine | 48T | EUR 398.4 |
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Description: Quantitative sandwich ELISA for measuring Human Serpin B5 (SERPINB5) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Serpin B5 (SERPINB5) |
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| KTE60698-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
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Description: Quantitative sandwich ELISA for measuring Human Serpin B5 (SERPINB5) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Serpin B5 (SERPINB5) |
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| KTE60698-96T | Abbkine | 96T | EUR 646.8 |
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Description: Quantitative sandwich ELISA for measuring Human Serpin B5 (SERPINB5) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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Human Serpin B3 Antibody (Biotin Conjugate) |
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| 32720-05121 | AssayPro | 150 ug | EUR 442.8 |
Human Serpin B8 Antibody (Biotin Conjugate) |
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| 32735-05121 | AssayPro | 150 ug | EUR 442.8 |
Human Serpin D1 Antibody (Biotin Conjugate) |
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| 32810-05121 | AssayPro | 150 ug | EUR 442.8 |
ELISA kit for Human Serpin B5 |
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| EK2905 | SAB | 96 tests | EUR 663.6 |
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Description: Enzyme-linked immunosorbent assay kit for quantification of Human Serpin B5 in samples from serum, plasma, tissue homogenates and other biological fluids. |
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Human Vaspin (Serpin A12) Antibody |
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| 30064-05111 | AssayPro | 150 ug | EUR 313.2 |
Serpin A6 Antibody |
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| 3906-100 | Biovision | each | EUR 379.2 |
Serpin A6 Antibody |
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| 3906-30T | Biovision | each | EUR 175.2 |
Serpin A6 antibody |
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| 70R-12181 | Fitzgerald | 100 ug | EUR 483.6 |
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Description: Rabbit polyclonal Serpin A6 antibody |
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Serpin B7 antibody |
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| 70R-50630 | Fitzgerald | 100 ul | EUR 292.8 |
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Description: Purified Polyclonal Serpin B7 antibody |
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Serpin A1 antibody |
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| 70R-50204 | Fitzgerald | 100 ul | EUR 292.8 |
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Description: Purified Polyclonal Serpin A1 antibody |
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Serpin B9 antibody |
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| 70R-50206 | Fitzgerald | 100 ul | EUR 292.8 |
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Description: Purified Polyclonal Serpin B9 antibody |
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Serpin B4 antibody |
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| 70R-50366 | Fitzgerald | 100 ul | EUR 292.8 |
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Description: Purified Polyclonal Serpin B4 antibody |
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Serpin A5 Antibody |
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| 34908-100ul | SAB | 100ul | EUR 302.4 |
Serpin A5 Antibody |
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| 34908-50ul | SAB | 50ul | EUR 224.4 |
Serpin A5 Antibody |
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| ABD4300 | Lifescience Market | 100 ug | EUR 525.6 |
Serpin A5 Antibody |
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| DF4300 | Affbiotech | 200ul | EUR 420 |
Human Maspin(serpin B5) ELISA kit |
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| E01M0026-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Human Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Maspin(serpin B5) ELISA kit |
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| E01M0026-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Human Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Maspin(serpin B5) ELISA kit |
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| E01M0026-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Human Maspin(serpin B5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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SERPINA4 (Serpin A4) Antibody |
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| 20-abx142217 | Abbexa |
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Serpin B3 / 4 Antibody |
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| 20-abx121729 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| 20-abx135864 | Abbexa |
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Serpin B8 (SERPINB8) Antibody |
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| 20-abx210287 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| abx237747-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin B8 (SERPINB8) Antibody |
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| abx237748-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin B9 (SERPINB9) Antibody |
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| abx237749-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin D1 (SERPIND1) Antibody |
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| abx237750-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin I2 (SERPINI2) Antibody |
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| abx237754-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin A8 (SERPINA8) Antibody |
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| 20-abx225020 | Abbexa |
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Serpin B3 (SERPINB3) Antibody |
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| 20-abx110205 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| 20-abx210574 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| 20-abx210575 | Abbexa |
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Serpin B3 (SERPINB3) Antibody |
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| 20-abx211337 | Abbexa |
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Serpin B3 (SERPINB3) Antibody |
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| 20-abx211338 | Abbexa |
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Serpin A1 (SERPINA1) Antibody |
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| 20-abx133762 | Abbexa |
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Serpin A3 (SERPINA3) Antibody |
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| 20-abx133770 | Abbexa |
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Serpin B4 (SERPINB4) Antibody |
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| abx122028-100ug | Abbexa | 100 ug | EUR 469.2 |
Serpin B8 (SERPINB8) Antibody |
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| abx122029-100ug | Abbexa | 100 ug | EUR 469.2 |
Serpin A5 (SERPINA5) Antibody |
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| abx147936-100ug | Abbexa | 100 ug | EUR 526.8 |
Serpin H1 (SERPINH1) Antibody |
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| 20-abx321407 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx321527 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| 20-abx322087 | Abbexa |
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Serpin B6 (SERPINB6) Antibody |
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| 20-abx322088 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| abx330656-100ul | Abbexa | 100 ul | EUR 510 |
Serpin B6 (SERPINB6) Antibody |
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| 20-abx115470 | Abbexa |
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Serpin B8 (SERPINB8) Antibody |
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| 20-abx115471 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx115472 | Abbexa |
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Serpin H1 (SERPINH1) Antibody |
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| 20-abx115477 | Abbexa |
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Serpin I2 (SERPINI2) Antibody |
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| 20-abx115479 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| abx031295-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin B9 (SERPINB9) Antibody |
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| abx031295-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin B8 (SERPINB8) Antibody |
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| abx031365-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin B8 (SERPINB8) Antibody |
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| abx031365-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin A9 (SERPINA9) Antibody |
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| abx025186-100ul | Abbexa | 100 ul | EUR 627.6 |
Serpin A9 (SERPINA9) Antibody |
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| abx025187-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin A9 (SERPINA9) Antibody |
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| abx025187-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin B6 (SERPINB6) Antibody |
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| abx036087-100ug | Abbexa | 100 ug | EUR 469.2 |
Serpin B9 (SERPINB9) Antibody |
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| abx036128-100ug | Abbexa | 100 ug | EUR 469.2 |
Serpin I2 (SERPINI2) Antibody |
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| abx029696-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin I2 (SERPINI2) Antibody |
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| abx029696-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin H1 (SERPINH1) Antibody |
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| abx033355-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin H1 (SERPINH1) Antibody |
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| abx033355-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin H1 (SERPINH1) Antibody |
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| abx033356-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin H1 (SERPINH1) Antibody |
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| abx033356-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin B8 (SERPINB8) Antibody |
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| 20-abx127044 | Abbexa |
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Serpin I2 (SERPINI2) Antibody |
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| 20-abx124373 | Abbexa |
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Serpin I2 (SERPINI2) Antibody |
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| 20-abx126534 | Abbexa |
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Serpin B3 (SERPINB3) Antibody |
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| 20-abx323774 | Abbexa |
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Serpin B4 (SERPINB4) Antibody |
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| 20-abx324075 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx328658 | Abbexa |
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Serpin B4 (SERPINB4) Antibody |
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| 20-abx334404 | Abbexa |
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Serpin D1 (SERPIND1) Antibody |
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| 20-abx320675 | Abbexa |
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Serpin B8 (SERPINB8) Antibody |
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| 20-abx339453 | Abbexa |
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Serpin H1 (Serpinh1) Antibody |
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| 20-abx319337 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| abx431610-200ul | Abbexa | 200 ul | EUR 460.8 |
Serpin B6 (SERPINB6) Antibody |
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| abx433266-200ul | Abbexa | 200 ul | EUR 460.8 |
Serpin B9 (SERPINB9) Antibody |
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| abx414334-01mg | Abbexa | 0.1 mg | EUR 526.8 |
Serpin H1 (SERPINH1) Antibody |
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| 20-abx001958 | Abbexa |
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Serpin A3 (SERPINA3) Antibody |
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| 20-abx007897 | Abbexa |
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Serpin B7 (SERPINB7) Antibody |
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| 20-abx008498 | Abbexa |
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Serpin B4 (SERPINB4) Antibody |
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| 20-abx008735 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx008866 | Abbexa |
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Serpin A1 (SERPINA1) Antibody |
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| 20-abx008868 | Abbexa |
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Serpin B3 (SERPINB3) Antibody |
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| 20-abx004151 | Abbexa |
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Serpin D1 (SERPIND1) Antibody |
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| 20-abx004485 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx004888 | Abbexa |
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Serpin B4 (SERPINB4) Antibody |
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| 20-abx014873 | Abbexa |
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Serpin B9 (SERPINB9) Antibody |
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| 20-abx014874 | Abbexa |
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Serpin G1 (SERPING1) Antibody |
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| 20-abx142218 | Abbexa |
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Serpin B8 (SERPINB8) Antibody |
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| 20-abx302456 | Abbexa |
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Serpin B3 Antibody (HRP) |
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| 20-abx108749 | Abbexa |
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Serpin B3 Antibody (FITC) |
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| 20-abx107329 | Abbexa |
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Serpin A12 (SERPINA12) Antibody |
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| 20-abx210286 | Abbexa |
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Serpin B12 (SERPINB12) Antibody |
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| abx237744-100ug | Abbexa | 100 ug | EUR 661.2 |
Serpin B13 (SERPINB13) Antibody |
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| abx237745-100ug | Abbexa | 100 ug | EUR 610.8 |
Serpin A11 (SERPINA11) Antibody |
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| abx218523-100ug | Abbexa | 100 ug | EUR 526.8 |
Serpin B12 (SERPINB12) Antibody |
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| abx218524-100ug | Abbexa | 100 ug | EUR 526.8 |
Serpin A11 (SERPINA11) Antibody |
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| 20-abx213899 | Abbexa |
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Serpin A11 (SERPINA11) Antibody |
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| 20-abx213900 | Abbexa |
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Serpin A12 (SERPINA12) Antibody |
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| 20-abx210572 | Abbexa |
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Serpin B12 (SERPINB12) Antibody |
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| 20-abx115466 | Abbexa |
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Serpin B13 (SERPINB13) Antibody |
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| 20-abx115467 | Abbexa |
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Serpin B12 (SERPINB12) Antibody |
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| abx030254-400ul | Abbexa | 400 ul | EUR 627.6 |
Serpin B12 (SERPINB12) Antibody |
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| abx030254-80l | Abbexa | 80 µl | EUR 343.2 |
Serpin B12 (SERPINB12) Antibody |
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| 20-abx323469 | Abbexa |
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Serpin A11 (SERPINA11) Antibody |
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| 20-abx323960 | Abbexa |
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Serpin A11 (SERPINA11) Antibody |
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| 20-abx338580 | Abbexa |
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Serpin A12 (SERPINA12) Antibody |
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| 20-abx320572 | Abbexa |
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Serpin A12 (SERPINA12) Antibody |
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| abx433262-200ul | Abbexa | 200 ul | EUR 460.8 |
Serpin A12 (SERPINA12) Antibody |
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| 20-abx006608 | Abbexa |
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Serpin B12 (SERPINB12) Antibody |
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| 20-abx308929 | Abbexa |
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Serpin B3 Antibody (Biotin) |
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| 20-abx105914 | Abbexa |
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Serpin B12 Antibody |
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| 47983-100ul | SAB | 100ul | EUR 302.4 |
Polyclonal Serpin B4 Antibody |
|||
| APG02973G | Leading Biology | 0.1ml | EUR 580.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Serpin B4 . This antibody is tested and proven to work in the following applications: |
|||
Serpin H1 (Serpinh1) Antibody (HRP) |
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| 20-abx319096 | Abbexa |
|
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Serpin A3-1 (SERPINA3) Antibody |
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| abx224104-100ug | Abbexa | 100 ug | EUR 493.2 |
Serpin B4 (SERPINB4) Antibody (HRP) |
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| 20-abx337655 | Abbexa |
|
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Serpin B8 (SERPINB8) Antibody (HRP) |
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| 20-abx305282 | Abbexa |
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Serpin H1 (Serpinh1) Antibody (FITC) |
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| 20-abx319097 | Abbexa |
|
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Serpin B4 (SERPINB4) Antibody (FITC) |
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| 20-abx337656 | Abbexa |
|
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Serpin B8 (SERPINB8) Antibody (FITC) |
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| 20-abx305283 | Abbexa |
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Serpin A11 (SERPINA11) Antibody (HRP) |
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| 20-abx337652 | Abbexa |
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Serpin B12 (SERPINB12) Antibody (HRP) |
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| 20-abx308930 | Abbexa |
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Human Serpin B3 AssayLite Antibody (RPE Conjugate) |
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| 32720-05151 | AssayPro | 150 ug | EUR 513.6 |
Human Serpin B3 AssayLite Antibody (APC Conjugate) |
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| 32720-05161 | AssayPro | 150 ug | EUR 513.6 |
Human Serpin B8 AssayLite Antibody (RPE Conjugate) |
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| 32735-05151 | AssayPro | 150 ug | EUR 513.6 |
Human Serpin B8 AssayLite Antibody (APC Conjugate) |
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| 32735-05161 | AssayPro | 150 ug | EUR 513.6 |
Human Serpin D1 AssayLite Antibody (RPE Conjugate) |
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| 32810-05151 | AssayPro | 150 ug | EUR 513.6 |
Human Serpin D1 AssayLite Antibody (APC Conjugate) |
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| 32810-05161 | AssayPro | 150 ug | EUR 513.6 |
Serpin H1 (Serpinh1) Antibody (Biotin) |
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| 20-abx319098 | Abbexa |
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Serpin A11 (SERPINA11) Antibody (FITC) |
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| 20-abx337653 | Abbexa |
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Serpin B4 (SERPINB4) Antibody (Biotin) |
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| 20-abx337657 | Abbexa |
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Remarkably, CwpFMs from pathogenic strains harbor a selected stretch of twenty residues intrinsically disordered, inserted between the SH3b3 and the catalytic area. This strongly suggests this linker as a marker of differentiation between B. cereus strains. We consider that our findings enhance our understanding of the pathogenicity of B. cereus whereas advancing each scientific prognosis and meals security.