ELISA kit for Rat Alpha-1-antitrypsin

Utility of directed evolution and back-to-consensus algorithms to human alpha1-antitrypsin results in diminished anti-protease exercise and augmented anti-inflammatory actions

 

• Primarily often known as an elastase inhibitor, human alpha1-antitrypsin additionally exerts anti-inflammatory and immunomodulatory results, each in vitro and in vivo.

Mouse Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA equipment

 

• Whereas the anti-protease mechanism of alpha1-antitrypsin is attributed to a selected protein area coined the reactive middle loop, anti-inflammatory and immunomodulatory loci inside the molecule stay to be recognized.

 

 

• Within the current examine, directed evolution and back-to-consensus algorithms have been utilized to human alpha1-antitrypsin. Six distinctive purposeful candidate websites have been recognized on the floor of the molecule; in manipulating these websites by level mutations, a recombinant mutant type of alpha1-antitrypsin was produced, depicting a requirement for websites outdoors the reactive middle loop as important for protease inhibition, and displaying enhanced anti-inflammatory actions.

Monoclonal SERPINA1 / Alpha 1 Antitrypsin Antibody (clone 9A1), Clone: 9A1

 

• Taken collectively, outcomes of the current examine set up a possible use for directed evolution in advancing our understanding of site-specific protein features, providing a platform for growth of context- and disease-specific alpha1-antitrypsin-based therapeutics.
  Key phrases: Alpha1-proteinase inhibitor; Protein construction; Recombinantprotein; SERPINA1.

 

Sheep Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx364213-96tests	Abbexa	96 tests	EUR 1111.2

Sheep Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA Kit
E14C0353-48wellsplate	BlueGene	48 wells plate	EUR 280

Sheep Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA Kit
E14C0353-96wellsplate	BlueGene	96 wells plate	EUR 405

Sheep Serpin Peptidase Inhibitor，Clade G (C1 Inhibitor)，Member1(SERPING1) ELISA Kit
E01A98161	BlueGene	96T	EUR 700

Mouse anti Human SerpinG1/C1 inhibitor/C1IN Monoclonal Antibody
MBS2543541-006mL	MyBiosource	0.06mL	EUR 250

Mouse anti Human SerpinG1/C1 inhibitor/C1IN Monoclonal Antibody
MBS2543541-012mL	MyBiosource	0.12mL	EUR 370

Mouse anti Human SerpinG1/C1 inhibitor/C1IN Monoclonal Antibody
MBS2543541-02mL	MyBiosource	0.2mL	EUR 550

Sheep C1S Inhibitor (SERPING1) ELISA Kit
MBS9905398-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 6725

Sheep C1S Inhibitor (SERPING1) ELISA Kit
MBS9905398-48StripWells	MyBiosource	48-Strip-Wells	EUR 550

Sheep C1S Inhibitor (SERPING1) ELISA Kit
MBS9905398-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 3420

Sheep C1S Inhibitor (SERPING1) ELISA Kit
MBS9905398-96StripWells	MyBiosource	96-Strip-Wells	EUR 765

Human C1 inhibitor/SerpinG1 ELISA Kit
MBS8123919-5x96Tests	MyBiosource	5x96Tests	EUR 2200

Human C1 inhibitor/SerpinG1 ELISA Kit
MBS8123919-96Tests	MyBiosource	96Tests	EUR 480

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx001435-100l	Abbexa	100 µl	EUR 400

Plasma Protease C1 Inhibitor (SERPING1) Antibody
20-abx001435	Abbexa	Ask for price Ask for price Ask for price Ask for price	20 ul 50 ul 100 ul 200 ul

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx001435-20l	Abbexa	20 µl	EUR 175

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx001435-50l	Abbexa	50 µl	EUR 275

Plasma Protease C1 Inhibitor (Serping1) Antibody
abx115476-100l	Abbexa	100 µl	EUR 612.5

Plasma Protease C1 Inhibitor (Serping1) Antibody
20-abx115476	Abbexa	Ask for price Ask for price	50 ul 150 ul

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx324635-100g	Abbexa	100 µg	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody
20-abx324635	Abbexa	Ask for price Ask for price	50 ug 100 ug

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx324635-50g	Abbexa	50 µg	EUR 187.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx339518-100g	Abbexa	100 µg	Ask for price

Plasma Protease C1 Inhibitor (SERPING1) Antibody
20-abx339518	Abbexa	Ask for price Ask for price	50 ul 100 ul

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx339518-20g	Abbexa	20 µg	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx339518-50g	Abbexa	50 µg	EUR 350

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx339693-100l	Abbexa	100 µl	EUR 350

Plasma Protease C1 Inhibitor (SERPING1) Antibody
20-abx339693	Abbexa	Ask for price Ask for price	50 ul 100 ul

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx339693-50l	Abbexa	50 µl	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx237753-100g	Abbexa	100 µg	EUR 350

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx237753-100ug	Abbexa	100 ug	EUR 610.8

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx302277-100g	Abbexa	100 µg	EUR 362.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody
20-abx302277	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	20 ug 50 ug 100 ug 200 ug 1 mg

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx302277-20g	Abbexa	20 µg	EUR 162.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody
abx302277-50g	Abbexa	50 µg	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody (HRP)
abx316008-100g	Abbexa	100 µg	EUR 362.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (HRP)
20-abx316008	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	20 ug 50 ug 100 ug 200 ug 1 mg

Plasma Protease C1 Inhibitor (SERPING1) Antibody (HRP)
abx316008-20g	Abbexa	20 µg	EUR 162.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (HRP)
abx316008-50g	Abbexa	50 µg	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody (FITC)
abx316009-100g	Abbexa	100 µg	EUR 362.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (FITC)
20-abx316009	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	20 ug 50 ug 100 ug 200 ug 1 mg

Plasma Protease C1 Inhibitor (SERPING1) Antibody (FITC)
abx316009-20g	Abbexa	20 µg	EUR 162.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (FITC)
abx316009-50g	Abbexa	50 µg	EUR 250

Plasma Protease C1 Inhibitor (SERPING1) Antibody (Biotin)
abx316010-100g	Abbexa	100 µg	EUR 362.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (Biotin)
20-abx316010	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	20 ug 50 ug 100 ug 200 ug 1 mg

Plasma Protease C1 Inhibitor (SERPING1) Antibody (Biotin)
abx316010-20g	Abbexa	20 µg	EUR 162.5

Plasma Protease C1 Inhibitor (SERPING1) Antibody (Biotin)
abx316010-50g	Abbexa	50 µg	EUR 250

Mouse Monoclonal [clone 3F4-1D9] (IgG2a,k) to Human SERPING1 / C1 Inhibitor
MBS246074-005mg	MyBiosource	0.05mg	EUR 595

Mouse Monoclonal [clone 3F4-1D9] (IgG2a,k) to Human SERPING1 / C1 Inhibitor
MBS246074-5x005mg	MyBiosource	5x0.05mg	EUR 2500

SERPING1 (untagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1
SC115553	Origene Technologies GmbH	10 µg	Ask for price

SERPING1 (untagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 2
SC302632	Origene Technologies GmbH	10 µg	Ask for price

Recombinant Human Plasma protease C1 inhibitor (SERPING1)
MBS954256-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1345

Recombinant Human Plasma protease C1 inhibitor (SERPING1)
MBS954256-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 1040

Recombinant Human Plasma protease C1 inhibitor (SERPING1)
MBS954256-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 1140

Recombinant Human Plasma protease C1 inhibitor (SERPING1)
MBS954256-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 1215

Recombinant Human Plasma protease C1 inhibitor (SERPING1)
MBS954256-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1295

Human SERPING1/ Plasma protease C1 inhibitor ELISA Kit
E2265Hu	Sunlong	1 Kit	EUR 515

SERPING1 (GFP-tagged) - Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1
RG203767	Origene Technologies GmbH	10 µg	Ask for price

SERPING1 (GFP-tagged) - Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 2
RG223112	Origene Technologies GmbH	10 µg	Ask for price

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx054430-100g	Abbexa	100 µg	Ask for price

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx054430-200g	Abbexa	200 µg	Ask for price

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx054430-50g	Abbexa	50 µg	EUR 562.5

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx054430-96tests	Abbexa	96 tests	EUR 943.2

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
CSB-EL021086HU-24T	Cusabio	1 plate of 24 wells	EUR 198

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
CSB-EL021086HU-48T	Cusabio	48T	EUR 290.06

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
1-CSB-EL021086HU	Cusabio	Ask for price Ask for price Ask for price	1 plate of 96 wells 5 plates of 96 wells each 10 plates of 96 wells each

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
CSB-EL021086HU-96T	Cusabio	96T	EUR 446.25

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx512301-96tests	Abbexa	96 tests	EUR 904.8

Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
abx253748-96tests	Abbexa	96 tests	EUR 904.8

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
AE19989HU-48T	Abebio	48T	EUR 325

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
AE19989HU-48Tests	Abebio	48 Tests	EUR 325

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
AE19989HU-96T	Abebio	96T	EUR 610

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
AE19989HU-96Tests	Abebio	96 Tests	EUR 610

Human Plasma protease C1 inhibitor,SERPING1 ELISA KIT
JOT-EKA0085Hu	Jotbody	96 wells	EUR 366.4

Human Plasma protease C1 inhibitor,SERPING1 ELISA KIT
EA0085Hu	Jiaxing Korain Biotech Ltd (BT Labs)	96 wells	EUR 458

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
EKC35035-48T	Biomatik Corporation	48T	EUR 474.04

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
EKC35035-5x96T	Biomatik Corporation	5x96T	EUR 3216.7

Human Plasma protease C1 inhibitor(SERPING1) ELISA kit
EKC35035-96T	Biomatik Corporation	96T	EUR 677.2

Human Plasma protease C1 inhibitor(SERPING1) Elisa Kit
EK713677	AFG Bioscience LLC	96 Wells	EUR 0.38

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
KTE60690-48T	Abbkine	48T	EUR 359

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
KTE60690-96T	Abbkine	96T	EUR 619

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
KTE60690-96T5	Abbkine	96 T×5	EUR 2809

Human Plasma protease C1 inhibitor (SERPING1) ELISA Kit
KTE60690-96T50	Abbkine	96 T×50	EUR 26209

Human Plasma protease C1 inhibitor, SERPING1 ELISA Kit
MBS1609824-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3460

 

Alpha-1 antitrypsin governs alcohol-related liver illness in mice and people

 

• The α-1-antitrypsin (or alpha-1-antitrypsin, A1AT) Z variant is the first reason for extreme A1AT deficiency and kinds polymeric chains that mixture within the endoplasmic reticulum of hepatocytes. Round 2%-5% of Europeans are heterozygous for the Z and WT M allele, and there’s proof of elevated danger of liver illness in comparison with MM A1AT people.

 

 

• Now we have proven that Z and M A1AT can copolymerize in cell fashions, however there was no direct statement of heteropolymer formation in vivo.